SLC9A9

Across TCGA cell cohorts, SLC9A9 mutation is significantly associated with the RNA expression of many other genes, with 29 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SLC9A9-associated genes across cancer lineages are GML, PRR30, and SSX3. Each is linked with SLC9A9 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC9A9-to-partner and partner-to-SLC9A9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GML grouped by SLC9A9-low versus SLC9A9-high in OESOPHAGUS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC9A9→partner) and Y-score (partner→SLC9A9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	GML →	+0.026	+4.906	<.001	.006	3	2
BLOOD_Leukemia	PRR30 →	+0.008	+3.684	.008	.004	3	2
PANCREAS	SSX3 →	+0.050	+4.491	<.001	.003	3	1
PANCREAS	SFT2D3 →	+0.899	+4.237	<.001	.006	3	1
OESOPHAGUS	TRIM64B →	+0.006	+4.906	<.001	.006	3	1
OESOPHAGUS	GOLGA6L6 →	+0.016	+4.906	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 29 associations by consensus.

GML by SLC9A9 expression — OESOPHAGUS

Explore this box plot interactively →