SLC9A8

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SLC9A8 mutation is significantly associated with the total protein of many other genes, with 23 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC9A8-associated genes across cancer lineages are Rad50, STAT3_pY705, and TFRC. Each is linked with SLC9A8 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC9A8-to-partner and partner-to-SLC9A8 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC9A8→partner) and Y-score (partner→SLC9A8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECRad50 →-0.182-2.308.041.03332
UCECSTAT3_pY705 →-0.297-1.807.002.02432
UCECTFRC →+0.521+2.459.007.01832
UCECTuberin →+0.263+1.700.007.04032
UCECASNS →+0.396+1.906.002.01532
UCECCaspase-7-cleavedD198 →+0.616+2.584.004.01032
Each partner links to its Q-omics profile. Showing the 6 strongest of 23 associations by consensus.

Exploration