Across TCGA patient cohorts, SLC9A6 mutation is significantly associated with the total protein of many other genes, with 33 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC9A6-associated genes across cancer lineages are ASNS, Caspase-7-cleavedD198, and 4E-BP1. Each is linked with SLC9A6 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC9A6-to-partner and partner-to-SLC9A6 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC9A6→partner) and Y-score (partner→SLC9A6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ASNS →	+0.304	+1.502	.005	.027	3	2
UCEC	Caspase-7-cleavedD198 →	+0.479	+1.945	.007	.002	3	2
UCEC	4E-BP1 →	+0.268	+1.906	.001	.014	3	2
UCEC	14-3-3_beta →	-0.087	-1.973	.004	.008	3	1
UCEC	EGFR_pY1068 →	-0.150	-1.152	.047	.048	3	1
UCEC	eIF4E →	+0.164	+1.754	.010	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 33 associations by consensus.

Exploration

SLC9A6 survival (RNA) · tumor vs normal (RNA) · all SLC9A6 data types