SLC9A5

Across TCGA patient cohorts, SLC9A5 mutation is significantly associated with the total protein of many other genes, with 43 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC9A5-associated genes across cancer lineages are Cyclin-B1, ASNS, and eIF4E. Each is linked with SLC9A5 in more than 3 cancer types. Because this analysis shows association rather than direction, both SLC9A5-to-partner and partner-to-SLC9A5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cyclin-B1 grouped by SLC9A5-low versus SLC9A5-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC9A5→partner) and Y-score (partner→SLC9A5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Cyclin-B1 →	+0.431	+1.662	.006	.010	3	4
SKCM	ASNS →	+0.474	+3.000	.014	.035	3	2
UCEC	eIF4E →	+0.118	+1.820	.049	.014	3	2
UCEC	INPP4B →	-0.221	-2.523	.016	<.001	3	2
UCEC	Rad50 →	-0.149	-1.222	.030	.011	3	2
UCEC	Rictor_pT1135 →	-0.058	-1.152	.045	.048	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 43 associations by consensus.

Cyclin-B1 by SLC9A5 expression — UCEC

Explore this box plot interactively →