SLC9A5

Across TCGA cell cohorts, SLC9A5 mutation is significantly associated with the mutation status of many other genes, with 4,470 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC9A5-associated genes across cancer lineages are IQSEC2, SEMA4F, and GSDMB. Each is linked with SLC9A5 in more than 3 cancer types. Because this analysis shows association rather than direction, both SLC9A5-to-partner and partner-to-SLC9A5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IQSEC2 grouped by SLC9A5-low versus SLC9A5-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC9A5→partner) and Y-score (partner→SLC9A5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	IQSEC2 →	+4.502	+5.066	.007	.007	1	4
SOFT_TISSUE	SEMA4F →	+5.502	+5.502	.003	.003	1	4
SKIN	GSDMB →	+5.392	+4.824	.004	.004	1	4
OVARY	CCN4 →	+4.977	+4.415	.007	.007	1	3
BLOOD_Leukemia	TBC1D17 →	+4.736	+5.560	.003	.003	1	3
SOFT_TISSUE	ATRNL1 →	+4.502	+5.066	.007	.007	1	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,470 associations by consensus.

IQSEC2 by SLC9A5 expression — SOFT_TISSUE

Explore this box plot interactively →