SLC9A4

Across TCGA patient cohorts, SLC9A4 mutation is significantly associated with the RNA expression of many other genes, with 3,339 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC9A4-associated genes across cancer lineages are CKAP2L, STIL, and LMNB2. Each is linked with SLC9A4 in more than 4 cancer types. Because this analysis shows association rather than direction, both SLC9A4-to-partner and partner-to-SLC9A4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CKAP2L grouped by SLC9A4-low versus SLC9A4-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC9A4→partner) and Y-score (partner→SLC9A4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	CKAP2L →	+0.755	+2.426	.002	.002	3	5
SKCM	STIL →	+0.338	+1.762	.003	.003	3	5
UCEC	LMNB2 →	+0.618	+2.115	<.001	<.001	3	4
UCEC	HASPIN →	+0.720	+2.115	<.001	<.001	3	4
LUAD	FANCA →	+0.593	+2.611	<.001	.005	3	4
LUAD	WDHD1 →	+0.570	+3.099	.007	<.001	2	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,339 associations by consensus.

CKAP2L by SLC9A4 expression — LUAD

Explore this box plot interactively →