SLC9A4

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, SLC9A4 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,108 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible SLC9A4-associated GO terms across cancer lineages are Vacuolar transport, Negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell, and Process utilizing autophagic mechanism. Each is linked with SLC9A4 in more than 7 cancer types. Because this analysis shows association rather than direction, both SLC9A4-to-partner and partner-to-SLC9A4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Vacuolar transport grouped by SLC9A4-low versus SLC9A4-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC9A4→partner) and Y-score (partner→SLC9A4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVARYVacuolar transport →+0.042+0.994.008.00238
OVARYNegative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell →+1.174+1.287<.001<.00138
SKINProcess utilizing autophagic mechanism →+0.032+0.082.007.00737
SKINAutophagy →+0.032+0.082.007.00737
OVARYResponse to unfolded protein →+0.067+0.993<.001<.00137
URINARY_TRACTResponse to steroid hormone →+0.066+1.033.001.00337
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,108 associations by consensus.

Vacuolar transport by SLC9A4 expression — OVARY

Box plot of Vacuolar transport in SLC9A4-low vs SLC9A4-high samples in OVARY.

Explore this box plot interactively →

Exploration