SLC9A4

Across TCGA cell cohorts, SLC9A4 mutation is significantly associated with the RNA expression of many other genes, with 282 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC9A4-associated genes across cancer lineages are BBS7, WBP2NL, and PRB1. Each is linked with SLC9A4 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC9A4-to-partner and partner-to-SLC9A4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BBS7 grouped by SLC9A4-low versus SLC9A4-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC9A4→partner) and Y-score (partner→SLC9A4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	BBS7 →	+0.578	+3.064	.003	.009	3	2
SOFT_TISSUE	WBP2NL →	+0.280	+3.607	<.001	.006	3	1
SOFT_TISSUE	PRB1 →	+0.306	+3.142	.003	.008	3	1
LUNG_NSCLC_LUAD	LILRA1 →	+0.016	+2.949	<.001	.001	3	1
LUNG_NSCLC_LUAD	SULT6B1 →	+0.548	+3.662	.002	.001	3	1
LUNG_NSCLC_LUAD	OCSTAMP →	+0.010	+3.343	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 282 associations by consensus.

BBS7 by SLC9A4 expression — LARGE_INTESTINE

Explore this box plot interactively →