SLC9A3R2

Across TCGA pan-cancer cohorts, SLC9A3R2 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated SLC9A3R2 data layer compared with 26 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher SLC9A3R2 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated SLC9A3R2 expression acts as an unfavorable survival marker, although some lineages such as CCRCC and COAD show a favorable association.

CCRCC, COAD, and LSCC are the cancer types where SLC9A3R2 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Median	III,IV	0.803	0.352	<.001	44	view →
COAD	DFS	Median	III,IV	1.000	0.889	.027	30	view →
LSCC	DFS	Median	II,III,IV	0.816	1.000	.001	11	view →
GBM	OS	Tertile	All	0.284	0.656	.008	10	view →
LUAD	DFS	Median	All	0.843	0.438	.014	7	view →
HNSC	OS	Quartile	II,III,IV	0.827	0.663	.024	4	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

SLC9A3R2–CCRCC (DFS)

Open the CCRCC breakdown →