SLC9A3R2

Across TCGA patient cohorts, SLC9A3R2 mutation is significantly associated with the RNA expression of many other genes, with 161 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC9A3R2-associated genes across cancer lineages are HBZP1, FAM96AP1, and SLC20A1P3. Each is linked with SLC9A3R2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC9A3R2-to-partner and partner-to-SLC9A3R2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HBZP1 grouped by SLC9A3R2-low versus SLC9A3R2-high in ESCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC9A3R2→partner) and Y-score (partner→SLC9A3R2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	HBZP1 →	+0.106	+5.247	<.001	.006	3	2
SARC	FAM96AP1 →	+0.171	+5.111	<.001	.008	3	2
BLCA	SLC20A1P3 →	+0.049	+7.640	<.001	.009	3	2
BRCA	MTND2P39 →	+0.044	+8.055	<.001	.007	3	1
SARC	RN7SL764P →	+0.185	+5.778	<.001	.003	3	1
SARC	RPL5P16 →	+0.069	+5.005	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 161 associations by consensus.

HBZP1 by SLC9A3R2 expression — ESCA

Explore this box plot interactively →