SLC9A3R1

Across TCGA pan-cancer cohorts, SLC9A3R1 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated SLC9A3R1 data layer compared with 25 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher SLC9A3R1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated SLC9A3R1 expression acts as an unfavorable survival marker, although some lineages such as LUAD and CCRCC show a favorable association.

LUAD, CCRCC, and LSCC are the cancer types where SLC9A3R1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Median	All	0.945	0.409	<.001	25	view →
CCRCC	OS	Median	III,IV	0.985	0.237	.017	10	view →
LSCC	DFS	Quartile	II,III,IV	1.000	0.759	.007	6	view →
HNSC	OS	Quartile	IV	0.865	0.500	.023	4	view →
GBM	OS	Median	All	0.296	0.453	.026	2	view →
PDAC	DFS	Quartile	All	0.467	0.233	.044	2	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

SLC9A3R1–LUAD (DFS)

Open the LUAD breakdown →