SLC9A3R1

Across TCGA patient cohorts, SLC9A3R1 mutation is significantly associated with the total protein of many other genes, with 7 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC9A3R1-associated genes across cancer lineages are SF2, VHL, and XBP1. Each is linked with SLC9A3R1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC9A3R1-to-partner and partner-to-SLC9A3R1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SF2 grouped by SLC9A3R1-low versus SLC9A3R1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC9A3R1→partner) and Y-score (partner→SLC9A3R1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SF2 →	-0.226	-2.986	<.001	.037	3	1
UCEC	VHL →	-1.409	-3.000	<.001	.036	3	1
UCEC	XBP1 →	-0.326	-2.986	<.001	.035	3	1
UCEC	CD49b →	-0.525	-2.980	.001	.036	2	1
UCEC	eIF4E →	+0.261	+3.000	.032	.037	1	1
UCEC	p62 Lck ligand →	+0.469	+3.000	.012	.037	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

SF2 by SLC9A3R1 expression — UCEC

Explore this box plot interactively →