SLC9A3

Across TCGA patient cohorts, SLC9A3 mutation is significantly associated with the total protein of many other genes, with 43 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC9A3-associated genes across cancer lineages are eIF4E, EGFR, and Caspase-7-cleavedD198. Each is linked with SLC9A3 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC9A3-to-partner and partner-to-SLC9A3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, eIF4E grouped by SLC9A3-low versus SLC9A3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC9A3→partner) and Y-score (partner→SLC9A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eIF4E →	+0.171	+2.807	.024	.003	3	3
COAD	EGFR →	+0.170	+1.882	.025	.031	3	2
COAD	Caspase-7-cleavedD198 →	+0.966	+3.186	.003	.009	3	2
UCEC	Cyclin-B1 →	+0.532	+3.169	.008	.018	3	2
SKCM	Rb_pS807_S811 →	+0.703	+3.000	.001	.035	3	2
UCEC	GATA3 →	+0.163	+1.939	.016	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 43 associations by consensus.

eIF4E by SLC9A3 expression — UCEC

Explore this box plot interactively →