SLC9A3

Across TCGA cell cohorts, SLC9A3 mutation is significantly associated with the RNA expression of many other genes, with 467 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC9A3-associated genes across cancer lineages are SPAG11A, GOLGA6C, and PIMREG. Each is linked with SLC9A3 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC9A3-to-partner and partner-to-SLC9A3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SPAG11A grouped by SLC9A3-low versus SLC9A3-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC9A3→partner) and Y-score (partner→SLC9A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	SPAG11A →	+0.024	+4.035	<.001	.006	3	2
LUNG_NSCLC_LUAD	GOLGA6C →	+0.060	+3.658	<.001	.005	3	2
LARGE_INTESTINE	PIMREG →	+0.877	+3.364	.003	.002	3	2
LARGE_INTESTINE	DCK →	+0.690	+3.364	<.001	.002	3	2
LARGE_INTESTINE	COX10 →	+0.559	+3.234	.005	.004	3	2
CNS	KCNA1 →	+0.552	+3.154	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 467 associations by consensus.

SPAG11A by SLC9A3 expression — CNS

Explore this box plot interactively →