SLC9A2

Across TCGA cell cohorts, SLC9A2 mutation is significantly associated with the RNA expression of many other genes, with 196 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC9A2-associated genes across cancer lineages are GAGE13, PIRT, and SSX7. Each is linked with SLC9A2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC9A2-to-partner and partner-to-SLC9A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GAGE13 grouped by SLC9A2-low versus SLC9A2-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC9A2→partner) and Y-score (partner→SLC9A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	GAGE13 →	+1.914	+3.266	<.001	<.001	3	2
BLOOD_Leukemia	PIRT →	+0.006	+4.874	.001	.002	3	1
STOMACH	SSX7 →	+0.433	+5.285	<.001	.003	3	1
BREAST	MAGEB5 →	+0.008	+4.196	<.001	.006	3	1
CNS	TAS2R7 →	+0.018	+4.981	.003	.008	3	1
CNS	OR4X2 →	+0.048	+4.981	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 196 associations by consensus.

GAGE13 by SLC9A2 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →