SLC9A1

Across TCGA cell cohorts, SLC9A1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,511 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible SLC9A1-associated GO terms across cancer lineages are Positive regulation of the force of heart contraction, Regulation of cardiac muscle cell membrane potential, and Maintenance of cell polarity. Each is linked with SLC9A1 in more than 16 cancer types. Because this analysis shows association rather than direction, both SLC9A1-to-partner and partner-to-SLC9A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of the force of heart contraction grouped by SLC9A1-low versus SLC9A1-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC9A1→partner) and Y-score (partner→SLC9A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Positive regulation of the force of heart contraction →	+1.630	+1.358	<.001	<.001	3	17
URINARY_TRACT	Regulation of cardiac muscle cell membrane potential →	+0.243	+1.548	<.001	<.001	3	16
OESOPHAGUS	Maintenance of cell polarity →	+0.164	+0.933	<.001	<.001	3	15
SOFT_TISSUE	Positive regulation of action potential →	+1.334	+0.915	<.001	.001	3	13
BONE	Regulation of the force of heart contraction →	+0.250	+1.097	<.001	<.001	3	13
BONE	Positive regulation of intracellular transport →	+0.093	+1.231	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,511 associations by consensus.

Positive regulation of the force of heart contraction by SLC9A1 expression — PANCREAS

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