SLC8A3

Across TCGA cell cohorts, SLC8A3 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,221 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible SLC8A3-associated GO terms across cancer lineages are Cytoplasmic translation, Regulation of syncytium formation by plasma membrane fusion, and Translational initiation. Each is linked with SLC8A3 in more than 8 cancer types. Because this analysis shows association rather than direction, both SLC8A3-to-partner and partner-to-SLC8A3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cytoplasmic translation grouped by SLC8A3-low versus SLC8A3-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC8A3→partner) and Y-score (partner→SLC8A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Cytoplasmic translation →	+0.089	+1.306	<.001	.001	3	8
UPPER_AERODIGESTIVE_TRACT	Regulation of syncytium formation by plasma membrane fusion →	+0.060	+0.038	.006	.005	2	9
OESOPHAGUS	Translational initiation →	+0.079	+0.153	.006	.009	3	7
UPPER_AERODIGESTIVE_TRACT	Regulation of myoblast fusion →	+0.075	+0.038	.001	.005	3	7
LUNG_SCLC	Negative regulation of myoblast fusion →	+0.115	+1.270	<.001	.003	2	7
LUNG_SCLC	Negative regulation of syncytium formation by plasma membrane fusion →	+0.115	+1.264	<.001	.004	2	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,221 associations by consensus.

Cytoplasmic translation by SLC8A3 expression — LUNG_SCLC

Explore this box plot interactively →