SLC8A2

Across TCGA cell cohorts, SLC8A2 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,276 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible SLC8A2-associated GO terms across cancer lineages are Positive regulation of translation, Regulation of TORC1 signaling, and Mitotic cytokinesis. Each is linked with SLC8A2 in more than 8 cancer types. Because this analysis shows association rather than direction, both SLC8A2-to-partner and partner-to-SLC8A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of translation grouped by SLC8A2-low versus SLC8A2-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC8A2→partner) and Y-score (partner→SLC8A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Positive regulation of translation →	+0.062	+0.469	.001	.004	2	9
OVARY	Regulation of TORC1 signaling →	+0.045	+0.728	<.001	<.001	3	8
SOFT_TISSUE	Mitotic cytokinesis →	+0.058	+0.809	.005	.004	3	8
BLOOD_Lymphoma	Epigenetic regulation of gene expression →	+0.045	+0.245	<.001	.006	3	8
OVARY	Positive regulation of monoatomic ion transport →	-0.077	-0.533	<.001	.004	3	8
PANCREAS	Regulation of transcription initiation by RNA polymerase II →	+0.056	+0.430	<.001	.004	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,276 associations by consensus.

Positive regulation of translation by SLC8A2 expression — PANCREAS

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