SLC7A9

Across TCGA patient cohorts, SLC7A9 mutation is significantly associated with the RNA expression of many other genes, with 3,692 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC7A9-associated genes across cancer lineages are VN1R69P, RN7SL750P, and KCTD9. Each is linked with SLC7A9 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC7A9-to-partner and partner-to-SLC7A9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, VN1R69P grouped by SLC7A9-low versus SLC7A9-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC7A9→partner) and Y-score (partner→SLC7A9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	VN1R69P →	+0.089	+7.640	<.001	.009	3	3
LUAD	RN7SL750P →	+0.362	+3.658	.001	.007	3	3
SKCM	KCTD9 →	+0.605	+2.443	.002	.001	3	3
UCEC	PSMC3IP →	+0.591	+2.061	<.001	<.001	3	3
SKCM	SCLT1 →	+0.377	+2.231	.006	.005	3	3
UCEC	EXOSC9 →	+0.423	+3.871	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,692 associations by consensus.

VN1R69P by SLC7A9 expression — BLCA

Explore this box plot interactively →