SLC7A9

Across TCGA cell cohorts, SLC7A9 mutation is significantly associated with the RNA expression of many other genes, with 56 significant associations in total. LUNG_NSCLC_LUSC shows the largest number of these associations.

The most reproducible SLC7A9-associated genes across cancer lineages are TPD52L3, GSG1L2, and LIM2. Each is linked with SLC7A9 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC7A9-to-partner and partner-to-SLC7A9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TPD52L3 grouped by SLC7A9-low versus SLC7A9-high in LUNG_NSCLC_LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC7A9→partner) and Y-score (partner→SLC7A9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	TPD52L3 →	+0.013	+4.643	<.001	.008	3	2
OVARY	GSG1L2 →	+0.032	+4.807	<.001	.003	3	2
BLOOD_Lymphoma	LIM2 →	+0.118	+4.350	.009	.005	3	2
BLOOD_Lymphoma	KRT82 →	+0.026	+4.643	<.001	.005	3	2
SOFT_TISSUE	KRTAP3-2 →	+0.557	+4.295	<.001	.002	3	1
SOFT_TISSUE	GRXCR1 →	+0.054	+4.392	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 56 associations by consensus.

TPD52L3 by SLC7A9 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →