SLC7A7

Across TCGA patient cohorts, SLC7A7 protein abundance is significantly associated with the RNA expression of many other genes, with 10,217 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SLC7A7-associated genes across cancer lineages are C2orf68, GRN, and CD4. Each is linked with SLC7A7 in more than 3 cancer types. Because this analysis shows association rather than direction, both SLC7A7-to-partner and partner-to-SLC7A7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SLC7A7 versus C2orf68 in BRCA, with a Pearson correlation of -0.72.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC7A7→partner) and Y-score (partner→SLC7A7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	C2orf68 →	-1.031	-1.179	<.001	.001	3	4
GBM	GRN →	+0.894	+0.732	.001	.006	3	4
GBM	CD4 →	+1.365	+0.957	<.001	<.001	3	4
GBM	CTSC →	+1.052	+0.713	.002	.008	3	4
LSCC	CHMP3 →	-0.359	-0.346	.001	.002	3	4
LSCC	CD80 →	+0.712	+0.477	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,217 associations by consensus.

SLC7A7 vs C2orf68 — BRCA

Explore this scatter interactively →