SLC7A7

Across TCGA patient cohorts, SLC7A7 mutation is significantly associated with the RNA expression of many other genes, with 2,132 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC7A7-associated genes across cancer lineages are RN7SL214P, MRPL20, and RN7SL402P. Each is linked with SLC7A7 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC7A7-to-partner and partner-to-SLC7A7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL214P grouped by SLC7A7-low versus SLC7A7-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC7A7→partner) and Y-score (partner→SLC7A7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RN7SL214P →	+0.055	+3.325	<.001	.004	3	2
SKCM	MRPL20 →	+0.428	+3.331	.002	.005	3	2
SKCM	RN7SL402P →	+0.120	+2.480	<.001	.005	3	2
UCEC	MEX3D →	+0.673	+2.928	<.001	<.001	3	2
UCEC	GAS2L1 →	+0.481	+1.847	.001	.009	3	2
UCEC	KIF18B →	+0.744	+1.869	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,132 associations by consensus.

RN7SL214P by SLC7A7 expression — SKCM

Explore this box plot interactively →