SLC7A7

Across TCGA cell cohorts, SLC7A7 mutation is significantly associated with the RNA expression of many other genes, with 37 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC7A7-associated genes across cancer lineages are OOSP2, OR10J1, and GGTLC2. Each is linked with SLC7A7 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC7A7-to-partner and partner-to-SLC7A7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OOSP2 grouped by SLC7A7-low versus SLC7A7-high in BREAST.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC7A7→partner) and Y-score (partner→SLC7A7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	OOSP2 →	+0.017	+4.781	<.001	.003	3	1
BREAST	OR10J1 →	+0.425	+4.781	<.001	.003	3	1
SKIN	GGTLC2 →	+0.022	+4.688	.007	<.001	3	1
SKIN	CCL21 →	+0.060	+4.054	.004	.004	3	1
SKIN	VSIG4 →	+0.017	+4.347	<.001	.001	3	1
SKIN	KRTAP5-5 →	+0.014	+4.437	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 37 associations by consensus.

OOSP2 by SLC7A7 expression — BREAST

Explore this box plot interactively →