SLC7A6

Across TCGA cell cohorts, SLC7A6 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,424 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SLC7A6-associated GO terms across cancer lineages are Glycine betaine transport, Nucleic acid transport, and RNA transport. Each is linked with SLC7A6 in more than 18 cancer types. Because this analysis shows association rather than direction, both SLC7A6-to-partner and partner-to-SLC7A6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Glycine betaine transport grouped by SLC7A6-low versus SLC7A6-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC7A6→partner) and Y-score (partner→SLC7A6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Glycine betaine transport →	+0.218	+1.257	<.001	<.001	3	19
BLOOD_Lymphoma	Nucleic acid transport →	+0.096	+1.371	<.001	<.001	3	16
BLOOD_Lymphoma	RNA transport →	+0.096	+1.371	<.001	<.001	3	16
SOFT_TISSUE	Signal transduction in response to DNA damage →	+0.056	+0.868	.005	.002	3	14
UPPER_AERODIGESTIVE_TRACT	Nuclear export →	+0.091	+1.206	.001	<.001	3	14
SOFT_TISSUE	RNA export from nucleus →	+0.121	+1.052	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,424 associations by consensus.

Glycine betaine transport by SLC7A6 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →