SLC7A4

Across TCGA patient cohorts, SLC7A4 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,669 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SLC7A4-associated proteins across cancer lineages are SEC24A, MDH2, and CXCL10. Each is linked with SLC7A4 in more than 3 cancer types. Because this analysis shows association rather than direction, both SLC7A4-to-partner and partner-to-SLC7A4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SLC7A4 versus SEC24A in LSCC, with a Pearson correlation of -0.31.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC7A4→partner) and Y-score (partner→SLC7A4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SEC24A →	-0.280	-0.611	<.001	.002	3	4
COAD	MDH2 →	+0.496	+1.022	<.001	<.001	3	4
PDAC	CXCL10 →	-1.181	-1.180	.001	<.001	3	4
COAD	GBP1 →	-0.769	-1.097	<.001	<.001	3	4
COAD	FAHD1 →	+0.579	+0.792	.001	.006	3	4
LSCC	GOT2 →	+0.642	+0.875	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,669 associations by consensus.

SLC7A4 vs SEC24A — LSCC

Explore this scatter interactively →