SLC7A1

Across TCGA patient cohorts, SLC7A1 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,867 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SLC7A1-associated proteins across cancer lineages are BRIX1, CUL4A, and EXOSC8. Each is linked with SLC7A1 in more than 5 cancer types. Because this analysis shows association rather than direction, both SLC7A1-to-partner and partner-to-SLC7A1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SLC7A1 versus BRIX1 in LUAD, with a Pearson correlation of 0.42.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC7A1→partner) and Y-score (partner→SLC7A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	BRIX1 →	+0.499	+0.738	<.001	<.001	3	6
BRCA	CUL4A →	+0.335	+0.710	<.001	<.001	3	6
GBM	EXOSC8 →	+0.285	+0.563	<.001	<.001	3	6
GBM	GTF2F2 →	+0.554	+0.627	<.001	<.001	3	6
LSCC	XRCC6_T455 →	+0.686	+0.790	<.001	<.001	3	6
LUAD	TMSB4X_T34 →	-0.872	-0.563	.001	.004	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,867 associations by consensus.

SLC7A1 vs BRIX1 — LUAD

Explore this scatter interactively →