SLC7A1

Across TCGA patient cohorts, SLC7A1 protein abundance is significantly associated with the RNA expression of many other genes, with 16,284 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SLC7A1-associated genes across cancer lineages are ABCA8, ABCA6, and KLHDC1. Each is linked with SLC7A1 in more than 5 cancer types. Because this analysis shows association rather than direction, both SLC7A1-to-partner and partner-to-SLC7A1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SLC7A1 versus ABCA8 in BRCA, with a Pearson correlation of -0.31.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC7A1→partner) and Y-score (partner→SLC7A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ABCA8 →	-1.035	-0.681	<.001	<.001	3	6
GBM	ABCA6 →	-0.937	-0.525	.001	.001	3	6
BRCA	KLHDC1 →	-0.709	-0.670	<.001	<.001	3	6
LSCC	HGF →	-0.764	-0.597	<.001	<.001	3	6
HNSC	CD80 →	-0.776	-0.529	.001	.001	3	5
GBM	CBLN3 →	-0.551	-0.658	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,284 associations by consensus.

SLC7A1 vs ABCA8 — BRCA

Explore this scatter interactively →