SLC7A1

Across TCGA patient cohorts, SLC7A1 mutation is significantly associated with the RNA expression of many other genes, with 3,228 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC7A1-associated genes across cancer lineages are RNU6-867P, LINC01895, and MORC1. Each is linked with SLC7A1 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC7A1-to-partner and partner-to-SLC7A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-867P grouped by SLC7A1-low versus SLC7A1-high in LGG.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC7A1→partner) and Y-score (partner→SLC7A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LGG	RNU6-867P →	+0.293	+7.977	<.001	.007	3	3
CESC	LINC01895 →	+0.297	+4.567	.002	.001	3	3
CESC	MORC1 →	+0.457	+4.162	<.001	.004	3	2
CESC	LINC01811 →	+0.429	+4.779	.002	.001	3	2
CESC	RNU7-173P →	+0.301	+4.384	<.001	.008	3	2
CESC	RNA5SP423 →	+0.234	+5.252	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,228 associations by consensus.

RNU6-867P by SLC7A1 expression — LGG

Explore this box plot interactively →