SLC7A1

Across TCGA cell cohorts, SLC7A1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,169 significant associations in total. BONE shows the largest number of these associations.

The most reproducible SLC7A1-associated GO terms across cancer lineages are Formate biosynthetic process, Ribosomal protein import into nucleus, and L-arginine import across plasma membrane. Each is linked with SLC7A1 in more than 12 cancer types. Because this analysis shows association rather than direction, both SLC7A1-to-partner and partner-to-SLC7A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Formate biosynthetic process grouped by SLC7A1-low versus SLC7A1-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC7A1→partner) and Y-score (partner→SLC7A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Formate biosynthetic process →	+0.143	+1.534	<.001	<.001	3	13
BREAST	Ribosomal protein import into nucleus →	+0.101	+0.749	.001	<.001	2	13
PANCREAS	L-arginine import across plasma membrane →	+0.690	+1.221	.003	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Viral translational termination-reinitiation →	+0.092	+1.087	.002	.005	3	10
LARGE_INTESTINE	L-leucine import across plasma membrane →	+0.167	+0.966	.001	.001	2	11
BLOOD_Leukemia	Ornithine transport →	+0.142	+0.644	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,169 associations by consensus.

Formate biosynthetic process by SLC7A1 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →