SLC6A8

Across TCGA patient cohorts, SLC6A8 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,662 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SLC6A8-associated proteins across cancer lineages are KDM3A, TBL3, and PGK1_S203. Each is linked with SLC6A8 in more than 5 cancer types. Because this analysis shows association rather than direction, both SLC6A8-to-partner and partner-to-SLC6A8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SLC6A8 versus KDM3A in BRCA, with a Pearson correlation of 0.40.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC6A8→partner) and Y-score (partner→SLC6A8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	KDM3A →	+0.493	+0.851	<.001	<.001	3	6
LSCC	TBL3 →	+0.241	+1.173	.002	.001	3	5
PDAC	PGK1_S203 →	+0.975	+0.976	<.001	<.001	3	5
LSCC	NKRF →	+0.521	+1.659	<.001	<.001	3	5
LUAD	USP40 →	-0.202	-0.821	.001	<.001	3	4
PDAC	RFX5 →	-0.215	-0.767	.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,662 associations by consensus.

SLC6A8 vs KDM3A — BRCA

Explore this scatter interactively →