SLC6A8

Across TCGA patient cohorts, SLC6A8 protein abundance is significantly associated with the RNA expression of many other genes, with 2,014 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SLC6A8-associated genes across cancer lineages are PNCK, PDZD11, and MICOS13. Each is linked with SLC6A8 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC6A8-to-partner and partner-to-SLC6A8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SLC6A8 versus PNCK in LSCC, with a Pearson correlation of 0.52.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC6A8→partner) and Y-score (partner→SLC6A8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PNCK →	+2.431	+0.930	<.001	<.001	3	3
LSCC	PDZD11 →	+0.532	+0.864	.002	.001	3	2
LSCC	MICOS13 →	+0.412	+0.668	<.001	.006	3	2
LSCC	COX5A →	+0.444	+0.607	.002	.001	3	2
CCRCC	MIR583HG →	+0.662	+0.514	<.001	.002	3	2
CCRCC	CERNA2 →	+2.089	+0.603	.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,014 associations by consensus.

SLC6A8 vs PNCK — LSCC

Explore this scatter interactively →