SLC6A8

Across TCGA cell cohorts, SLC6A8 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,893 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible SLC6A8-associated GO terms across cancer lineages are Creatine transmembrane transport, Creatine metabolic process, and Gamma-aminobutyric acid transport. Each is linked with SLC6A8 in more than 19 cancer types. Because this analysis shows association rather than direction, both SLC6A8-to-partner and partner-to-SLC6A8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Creatine transmembrane transport grouped by SLC6A8-low versus SLC6A8-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC6A8→partner) and Y-score (partner→SLC6A8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Creatine transmembrane transport →	+1.668	+3.001	<.001	<.001	3	20
URINARY_TRACT	Creatine metabolic process →	+1.017	+2.192	<.001	<.001	3	17
LUNG_SCLC	Gamma-aminobutyric acid transport →	+1.282	+2.136	<.001	<.001	3	15
BLOOD_Leukemia	scaRNA localization to Cajal body →	+0.047	+1.744	.001	.002	3	9
BLOOD_Lymphoma	Purine ribonucleoside triphosphate metabolic process →	+0.062	+1.112	<.001	<.001	3	8
OVARY	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process →	+0.034	+1.540	.004	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,893 associations by consensus.

Creatine transmembrane transport by SLC6A8 expression — LUNG_SCLC

Explore this box plot interactively →