SLC6A7

Across TCGA patient cohorts, SLC6A7 protein abundance is significantly associated with the RNA expression of many other genes, with 9,359 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible SLC6A7-associated genes across cancer lineages are PRODH, SOX10, and SEPTIN3. Each is linked with SLC6A7 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC6A7-to-partner and partner-to-SLC6A7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SLC6A7 versus PRODH in GBM, with a Pearson correlation of 0.32.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC6A7→partner) and Y-score (partner→SLC6A7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PRODH →	+1.025	+0.665	<.001	.002	3	1
GBM	SOX10 →	+1.270	+0.578	.001	.001	3	1
GBM	SEPTIN3 →	+1.360	+0.930	<.001	<.001	3	1
GBM	NEFH →	+1.603	+1.003	<.001	<.001	3	1
GBM	RASD2 →	+0.544	+0.608	<.001	<.001	3	1
GBM	SYNGR1 →	+0.967	+0.954	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,359 associations by consensus.

SLC6A7 vs PRODH — GBM

Explore this scatter interactively →