SLC6A7

Across TCGA cell cohorts, SLC6A7 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,519 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC6A7-associated GO terms across cancer lineages are Steroid hormone secretion, B cell differentiation, and Striatal medium spiny neuron differentiation. Each is linked with SLC6A7 in more than 6 cancer types. Because this analysis shows association rather than direction, both SLC6A7-to-partner and partner-to-SLC6A7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Steroid hormone secretion grouped by SLC6A7-low versus SLC6A7-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC6A7→partner) and Y-score (partner→SLC6A7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Steroid hormone secretion →	+1.066	+0.799	<.001	<.001	3	7
LARGE_INTESTINE	B cell differentiation →	+0.057	+1.172	<.001	<.001	3	5
KIDNEY	Striatal medium spiny neuron differentiation →	+1.003	+0.029	<.001	.005	3	4
KIDNEY	Regulation of follicle-stimulating hormone secretion →	+1.116	+0.030	<.001	.003	3	4
KIDNEY	Positive regulation of follicle-stimulating hormone secretion →	+1.116	+0.030	<.001	.003	3	4
KIDNEY	Negative regulation of follicle-stimulating hormone secretion →	+1.051	+0.030	<.001	.003	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,519 associations by consensus.

Steroid hormone secretion by SLC6A7 expression — LARGE_INTESTINE

Explore this box plot interactively →