SLC6A6

Across TCGA patient cohorts, SLC6A6 protein abundance is significantly associated with the RNA expression of many other genes, with 8,510 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SLC6A6-associated genes across cancer lineages are ZNF684, RPL26P20, and ZNF302. Each is linked with SLC6A6 in more than 3 cancer types. Because this analysis shows association rather than direction, both SLC6A6-to-partner and partner-to-SLC6A6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SLC6A6 versus ZNF684 in BRCA, with a Pearson correlation of -0.64.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC6A6→partner) and Y-score (partner→SLC6A6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ZNF684 →	-0.741	-0.602	.001	.008	3	4
LUAD	RPL26P20 →	-0.489	-0.478	.005	.004	3	3
BRCA	ZNF302 →	-1.332	-0.754	<.001	<.001	3	3
UCEC	ZNF30 →	-0.565	-0.494	.001	.006	3	3
LSCC	AGER →	-1.259	-0.623	.001	.007	3	3
LUAD	TRIM2 →	+0.950	+0.451	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,510 associations by consensus.

SLC6A6 vs ZNF684 — BRCA

Explore this scatter interactively →