SLC6A6

Across TCGA cell cohorts, SLC6A6 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,215 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible SLC6A6-associated GO terms across cancer lineages are Gamma-aminobutyric acid import, Gamma-aminobutyric acid transport, and Positive regulation of cell-matrix adhesion. Each is linked with SLC6A6 in more than 19 cancer types. Because this analysis shows association rather than direction, both SLC6A6-to-partner and partner-to-SLC6A6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Gamma-aminobutyric acid import grouped by SLC6A6-low versus SLC6A6-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC6A6→partner) and Y-score (partner→SLC6A6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Gamma-aminobutyric acid import →	+1.505	+2.059	<.001	<.001	3	20
LUNG_SCLC	Gamma-aminobutyric acid transport →	+1.449	+1.528	<.001	<.001	3	14
SKIN	Positive regulation of cell-matrix adhesion →	+0.110	+1.129	<.001	.002	3	12
LUNG_NSCLC_LUAD	Taurine transmembrane transport →	+0.157	+1.258	.001	<.001	3	11
SKIN	Retrograde transport, endosome to Golgi →	+0.077	+1.441	<.001	.001	3	11
LUNG_NSCLC_LUAD	Alkanesulfonate transmembrane transport →	+0.157	+1.258	.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,215 associations by consensus.

Gamma-aminobutyric acid import by SLC6A6 expression — OVARY

Explore this box plot interactively →