SLC6A4

Across TCGA patient cohorts, SLC6A4 protein abundance is significantly associated with the protein abundance of many other proteins, with 10,426 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible SLC6A4-associated proteins across cancer lineages are UTRN_S3240, ARHGAP6_S637, and RADIL_S598. Each is linked with SLC6A4 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC6A4-to-partner and partner-to-SLC6A4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SLC6A4 versus UTRN_S3240 in LSCC, with a Pearson correlation of 0.59.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC6A4→partner) and Y-score (partner→SLC6A4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	UTRN_S3240 →	+1.853	+1.001	<.001	.005	3	2
LSCC	ARHGAP6_S637 →	+0.602	+0.657	<.001	<.001	3	2
LUAD	RADIL_S598 →	+0.477	+0.742	<.001	<.001	3	2
LSCC	ARL16 →	-0.482	-0.786	<.001	<.001	3	1
LUAD	RBMS1_S176 →	+0.388	+0.516	<.001	<.001	3	1
LUAD	RBP2 →	+0.457	+0.536	.003	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,426 associations by consensus.

SLC6A4 vs UTRN_S3240 — LSCC

Explore this scatter interactively →