SLC6A3

Across TCGA patient cohorts, SLC6A3 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,026 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible SLC6A3-associated GO terms across cancer lineages are Protein folding, Cellular response to hydrogen peroxide, and Nucleobase-containing compound transport. Each is linked with SLC6A3 in more than 14 cancer types. Because this analysis shows association rather than direction, both SLC6A3-to-partner and partner-to-SLC6A3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein folding grouped by SLC6A3-low versus SLC6A3-high in UCS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC6A3→partner) and Y-score (partner→SLC6A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCS	Protein folding →	+0.038	+0.576	<.001	.001	3	14
SCLC	Cellular response to hydrogen peroxide →	+0.073	+1.984	<.001	<.001	2	14
THYM	Nucleobase-containing compound transport →	+0.038	+1.568	<.001	<.001	3	13
ESCA	Negative regulation of kinase activity →	+0.066	+0.320	<.001	.002	1	15
THYM	Response to endoplasmic reticulum stress →	+0.025	+1.381	.005	.001	2	14
UCS	Aorta morphogenesis →	+0.068	+0.526	.002	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,026 associations by consensus.

Protein folding by SLC6A3 expression — UCS

Explore this box plot interactively →