SLC6A2

Across TCGA patient cohorts, SLC6A2 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,126 significant associations in total. PRAD shows the largest number of these associations.

The most reproducible SLC6A2-associated GO terms across cancer lineages are Mesenchymal cell differentiation, Regulation of animal organ morphogenesis, and Regulation of actin filament bundle assembly. Each is linked with SLC6A2 in more than 12 cancer types. Because this analysis shows association rather than direction, both SLC6A2-to-partner and partner-to-SLC6A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mesenchymal cell differentiation grouped by SLC6A2-low versus SLC6A2-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC6A2→partner) and Y-score (partner→SLC6A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Mesenchymal cell differentiation →	+0.061	+0.224	<.001	<.001	3	13
STAD	Regulation of animal organ morphogenesis →	+0.049	+0.186	<.001	<.001	3	13
STAD	Regulation of actin filament bundle assembly →	+0.091	+0.285	<.001	<.001	3	13
TGCT	Embryonic appendage morphogenesis →	+0.045	+0.236	<.001	<.001	3	13
TGCT	Bone morphogenesis →	+0.049	+0.292	<.001	<.001	3	13
ESCA	Regulation of protein localization to lysosome →	+0.059	+0.628	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,126 associations by consensus.

Mesenchymal cell differentiation by SLC6A2 expression — STAD

Explore this box plot interactively →