SLC6A2

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SLC6A2 protein abundance is significantly associated with the RNA expression of many other genes, with 38 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC6A2-associated genes across cancer lineages are ZNF684, PACSIN1, and CD101. Each is linked with SLC6A2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC6A2-to-partner and partner-to-SLC6A2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SLC6A2 versus ZNF684 in UCEC, with a Pearson correlation of 0.47.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC6A2→partner) and Y-score (partner→SLC6A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECZNF684 →+0.476+0.797.002.00731
UCECPACSIN1 →+1.393+1.142<.001.00831
UCECCD101 →+1.028+0.861.009.00631
UCECPDE6H →+0.380+1.775<.001<.00131
UCECTDRD9 →+0.820+1.565.001.00931
UCECC7orf33 →+0.155+1.451.001.00831
Each partner links to its Q-omics profile. Showing the 6 strongest of 38 associations by consensus.

SLC6A2 vs ZNF684 — UCEC

Per-sample scatter of SLC6A2 vs ZNF684 in UCEC (Pearson r = 0.47).

Explore this scatter interactively →

Exploration