SLC6A19

Across TCGA patient cohorts, SLC6A19 mutation is significantly associated with the total protein of many other genes, with 47 significant associations in total. COAD shows the largest number of these associations.

The most reproducible SLC6A19-associated genes across cancer lineages are RAD51, Stathmin, and ASNS. Each is linked with SLC6A19 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC6A19-to-partner and partner-to-SLC6A19 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RAD51 grouped by SLC6A19-low versus SLC6A19-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC6A19→partner) and Y-score (partner→SLC6A19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RAD51 →	+0.173	+3.000	.003	.034	3	3
COAD	Stathmin →	+0.128	+1.708	.029	.026	3	3
COAD	ASNS →	+0.577	+1.708	<.001	.026	3	3
COAD	c-Kit →	-0.570	-2.700	.013	.005	3	2
UCEC	eIF4E →	+0.194	+2.906	.007	.001	3	2
COAD	14-3-3_epsilon →	+0.182	+3.484	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 47 associations by consensus.

RAD51 by SLC6A19 expression — COAD

Explore this box plot interactively →