SLC6A19

Across TCGA cell cohorts, SLC6A19 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,088 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SLC6A19-associated GO terms across cancer lineages are Regulation of mitochondrion organization, Renal D-glucose absorption, and Cholesterol homeostasis. Each is linked with SLC6A19 in more than 3 cancer types. Because this analysis shows association rather than direction, both SLC6A19-to-partner and partner-to-SLC6A19 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of mitochondrion organization grouped by SLC6A19-low versus SLC6A19-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC6A19→partner) and Y-score (partner→SLC6A19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Regulation of mitochondrion organization →	+0.044	+0.015	.001	<.001	2	4
LIVER	Renal D-glucose absorption →	+2.076	+3.612	<.001	.001	3	3
LIVER	Cholesterol homeostasis →	+0.150	+2.767	<.001	.008	3	3
BLOOD_Leukemia	Positive regulation of execution phase of apoptosis →	+0.076	+1.990	<.001	<.001	3	3
BLOOD_Leukemia	Regulation of phenotypic switching →	+0.099	+1.330	<.001	.003	3	3
BLOOD_Leukemia	Regulation of glycoprotein metabolic process →	+0.073	+1.784	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,088 associations by consensus.

Regulation of mitochondrion organization by SLC6A19 expression — BREAST

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