SLC6A15

Across TCGA patient cohorts, SLC6A15 mutation is significantly associated with the RNA expression of many other genes, with 5,220 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC6A15-associated genes across cancer lineages are NDC80, SLC7A5, and SLBP. Each is linked with SLC6A15 in more than 4 cancer types. Because this analysis shows association rather than direction, both SLC6A15-to-partner and partner-to-SLC6A15 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NDC80 grouped by SLC6A15-low versus SLC6A15-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC6A15→partner) and Y-score (partner→SLC6A15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	NDC80 →	+0.851	+3.918	.003	<.001	3	5
UCEC	SLC7A5 →	+0.610	+1.592	.004	.005	3	5
UCEC	SLBP →	+0.516	+1.747	<.001	<.001	3	5
UCEC	PARPBP →	+0.398	+1.736	.007	<.001	3	5
LUAD	BIRC5 →	+1.106	+2.700	.001	.006	3	4
LUAD	KIF4A →	+0.870	+2.807	.006	.003	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,220 associations by consensus.

NDC80 by SLC6A15 expression — LUAD

Explore this box plot interactively →