SLC6A15

Across TCGA cell cohorts, SLC6A15 mutation is significantly associated with the RNA expression of many other genes, with 29 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC6A15-associated genes across cancer lineages are OR3A3, C1orf87, and IL3. Each is linked with SLC6A15 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC6A15-to-partner and partner-to-SLC6A15 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR3A3 grouped by SLC6A15-low versus SLC6A15-high in PANCREAS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC6A15→partner) and Y-score (partner→SLC6A15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	OR3A3 →	+0.025	+5.000	<.001	.006	3	1
PANCREAS	C1orf87 →	+0.059	+5.000	<.001	.006	3	1
PANCREAS	IL3 →	+0.023	+5.614	<.001	.002	3	1
PANCREAS	GRIFIN →	+0.075	+5.000	<.001	.006	3	1
LARGE_INTESTINE	PRSS54 →	+0.026	+3.023	<.001	.002	3	1
LARGE_INTESTINE	RSPH6A →	+0.098	+3.688	.004	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 29 associations by consensus.

OR3A3 by SLC6A15 expression — PANCREAS

Explore this box plot interactively →