SLC6A14

Across TCGA cell cohorts, SLC6A14 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,743 significant associations in total. PANCREAS shows the largest number of these associations.

The most reproducible SLC6A14-associated GO terms across cancer lineages are Regulation of endoplasmic reticulum unfolded protein response, Protein localization to cell surface, and Viral budding via host ESCRT complex. Each is linked with SLC6A14 in more than 6 cancer types. Because this analysis shows association rather than direction, both SLC6A14-to-partner and partner-to-SLC6A14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of endoplasmic reticulum unfolded protein response grouped by SLC6A14-low versus SLC6A14-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC6A14→partner) and Y-score (partner→SLC6A14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Regulation of endoplasmic reticulum unfolded protein response →	+0.107	+1.217	<.001	.005	3	7
URINARY_TRACT	Protein localization to cell surface →	+0.142	+1.619	<.001	.003	3	7
UPPER_AERODIGESTIVE_TRACT	Viral budding via host ESCRT complex →	+0.072	+1.133	<.001	.007	3	7
LUNG_NSCLC_LUAD	Muscle contraction →	+0.030	+1.035	<.001	.007	3	7
OVARY	Positive regulation of chromatin binding →	+0.263	+0.530	<.001	.002	3	6
STOMACH	Epidermis development →	+0.086	+1.608	.004	.005	2	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,743 associations by consensus.

Regulation of endoplasmic reticulum unfolded protein response by SLC6A14 expression — URINARY_TRACT

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