SLC6A12-AS1

Across TCGA pan-cancer cohorts, SLC6A12-AS1 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated SLC6A12-AS1 data layer.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher SLC6A12-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated SLC6A12-AS1 expression acts as an unfavorable survival marker, although some lineages such as LUAD and ESCA show a favorable association.

COAD, LUAD, and UCEC are the cancer types where SLC6A12-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	OS	Tertile	II,III,IV	0.325	0.629	<.001	84	view →
LUAD	OS	Quartile	II,III,IV	0.729	0.501	.001	69	view →
UCEC	OS	Quartile	All	0.471	0.771	<.001	62	view →
ESCA	DFS	Median	III,IV	0.560	0.308	.003	60	view →
ACC	OS	Tertile	III,IV	0.390	0.821	<.001	48	view →
LGG	DFS	Median	All	0.781	0.879	<.001	40	view →
LUSC	OS	Tertile	IV	0.057	0.786	.017	36	view →
KICH	DFS	Median	II,III,IV	1.000	0.589	.006	35	view →
DLBC	OS	Tertile	III,IV	0.272	1.000	.017	28	view →
HNSC	OS	Quartile	IV	0.541	0.373	.021	23	view →
OV	OS	Median	II,III,IV	0.801	0.880	.001	22	view →
KIRP	OS	Quartile	All	0.979	0.876	.010	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

SLC6A12-AS1–COAD (OS)

Open the COAD breakdown →