Across TCGA patient cohorts, SLC6A10P mutation is significantly associated with the total protein of many other genes, with 23 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC6A10P-associated genes across cancer lineages are EGFR_pY1068, A-Raf_pS299, and Fibronectin. Each is linked with SLC6A10P in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC6A10P-to-partner and partner-to-SLC6A10P results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC6A10P→partner) and Y-score (partner→SLC6A10P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	EGFR_pY1068 →	-0.243	-2.459	.045	.020	3	1
UCEC	A-Raf_pS299 →	-0.226	-3.169	<.001	.018	3	1
UCEC	Fibronectin →	-0.374	-3.584	.018	.002	3	1
UCEC	FoxM1 →	+0.297	+3.009	.017	.019	3	1
UCEC	FOXO3a_pS318_S321 →	-0.167	-3.321	.005	.009	3	1
UCEC	NF2 →	+0.273	+2.999	.009	.035	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 23 associations by consensus.

Exploration

SLC6A10P survival (RNA) · tumor vs normal (RNA) · all SLC6A10P data types