SLC6A1

Across TCGA patient cohorts, SLC6A1 protein abundance is significantly associated with the RNA expression of many other genes, with 6,013 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SLC6A1-associated genes across cancer lineages are MDFIC, NIBAN2, and NLRP12. Each is linked with SLC6A1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC6A1-to-partner and partner-to-SLC6A1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SLC6A1 versus MDFIC in LUAD, with a Pearson correlation of -0.47.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC6A1→partner) and Y-score (partner→SLC6A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	MDFIC →	-0.850	-1.016	.002	.007	3	2
GBM	NIBAN2 →	-0.612	-0.687	<.001	<.001	3	2
LUAD	NLRP12 →	-0.624	-0.914	.003	.005	3	2
LUAD	CLCF1 →	-0.871	-0.992	.003	.007	3	2
LUAD	LINC02398 →	+3.025	+1.004	.001	.003	3	2
GBM	CSTA →	-0.988	-0.855	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,013 associations by consensus.

SLC6A1 vs MDFIC — LUAD

Explore this scatter interactively →