SLC6A1

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SLC6A1 protein abundance is significantly associated with the protein abundance of many other proteins, with 12,615 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SLC6A1-associated proteins across cancer lineages are STK32C_S18, TOE1_S428, and TPPP_T14. Each is linked with SLC6A1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC6A1-to-partner and partner-to-SLC6A1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SLC6A1 versus STK32C_S18 in GBM, with a Pearson correlation of 0.65.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC6A1→partner) and Y-score (partner→SLC6A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMSTK32C_S18 →+0.642+0.824<.001<.00132
GBMTOE1_S428 →+0.610+1.082.001<.00132
GBMTPPP_T14 →+0.865+1.047<.001<.00132
GBMRAP1GAP2_S613 →+1.003+0.759<.001<.00132
GBMRALGAPA1_S1478 →+0.979+0.843<.001<.00132
LUADAKAP9_S1327 →-1.154-0.841.005<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 12,615 associations by consensus.

SLC6A1 vs STK32C_S18 — GBM

Per-sample scatter of SLC6A1 vs STK32C_S18 in GBM (Pearson r = 0.65).

Explore this scatter interactively →

Exploration