SLC6A1

Across TCGA cell cohorts, SLC6A1 RNA expression is significantly associated with the go_rna of many other GO terms, with 667 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible SLC6A1-associated GO terms across cancer lineages are Energy derivation by oxidation of organic compounds, Regulation of myoblast fusion, and Retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum. Each is linked with SLC6A1 in more than 5 cancer types. Because this analysis shows association rather than direction, both SLC6A1-to-partner and partner-to-SLC6A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Energy derivation by oxidation of organic compounds grouped by SLC6A1-low versus SLC6A1-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC6A1→partner) and Y-score (partner→SLC6A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Energy derivation by oxidation of organic compounds →	+0.050	+0.400	<.001	.005	3	6
SOFT_TISSUE	Regulation of myoblast fusion →	+0.067	+0.387	<.001	.007	3	6
BREAST	Retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum →	+0.053	+0.025	.006	.007	3	5
BREAST	Regulation of protein localization to mitochondrion →	+0.096	+0.022	.002	.003	3	5
BREAST	Post-translational protein targeting to membrane, translocation →	+0.090	+0.023	<.001	.002	3	5
SKIN	Negative regulation of myoblast fusion →	+0.081	+0.119	<.001	.005	2	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 667 associations by consensus.

Energy derivation by oxidation of organic compounds by SLC6A1 expression — SOFT_TISSUE

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